If your experiencing long initial page load times and your servers are configured so they can't connect out to the internet, you can reduce this time by either allowing the servers access to crl.microsoft.com or by deselecting the 'Check for publisher's certificate revocation' option from within Internet Explorer. The Internet Explorer option can be found under the Tools menu, then Internet Options:
Another option is to add a host file entry so that crl.microsoft.com points to the localhost (127.0.0.1)